Sirolimus (Rapamycin) for Slow-Flow Malformations in Children

Maruani, A.; Tavernier, Elsa; Boccara, O.; Mazereeuw‐Hautier, J.; Leducq, Sophie; Bessis, D.; Guibaud, Laurent; Vabres, P.; Carmignac, Virginie; Mallet, S.; Barbarot, S.; Chiavérini, C.; Droitcourt, C.; Bursztejn, A.‐C.; Lengellé, Céline; Woillard, Jean‐Baptiste; Herbreteau, Denis; Le Touze, Anne; Joly, Aline; Léauté‐Labrèze, C.; Powell, Julie; Bourgoin, Hélène; Gissot, Valérie; Giraudeau, Bruno; Morel, Baptiste

doi:10.1001/jamadermatol.2021.3459

Public

Sirolimus (Rapamycin) for Slow-Flow Malformations in Children

Published in JAMA Dermatology • Sep 15, 2021

Authors:

A. Maruani

Elsa Tavernier

O. Boccara

Abstract

IMPORTANCE: Sirolimus is increasingly being used to treat various vascular anomalies, although evidence of its efficacy is lacking. OBJECTIVE: To assess the efficacy and safety of sirolimus for children with slow-flow vascular malformations to better delineate the indications for treatment. DESIGN, ...

Subject

Medicine

Observational study

Vascular malformation

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