Microbiome-pathogen interactions drive epidemiological dynamics of antibiotic resistance: A modeling study applied to nosocomial pathogen control

R. Smith, David; Temime, Laura; Opatowski, Lulla

doi:10.7554/elife.68764

Public

Microbiome-pathogen interactions drive epidemiological dynamics of antibiotic resistance: A modeling study applied to nosocomial pathogen control

Published in eLife • Sep 13, 2021

Authors:

David R. Smith

Laura Temime

Lulla Opatowski

Abstract

The human microbiome can protect against colonization with pathogenic antibiotic-resistant bacteria (ARB), but its impacts on the spread of antibiotic resistance are poorly understood. We propose a mathematical modeling framework for ARB epidemiology formalizing within-host ARB-microbiome competitio...

Subject

Microbiome

Antibiotic resistance

Antibiotics

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