Ten millennia of hepatitis B virus evolution

Kocher, Arthur; Papac, Luka; Barquera, Rodrigo; M. Key, Felix; A. Spyrou, Maria; Hübler, Ron; B. Rohrlach, Adam; Aron, Franziska; Stahl, Raphaela; Wissgott, Antje; van Bömmel, Florian; Pfefferkorn, Maria; Mittnik, Alissa; Villalba-Mouco, Vanessa; U. Neumann, Gunnar; Rivollat, Maïté; S. van de Loosdrecht, Marieke; Majander, Kerttu; I. Tukhbatova, Rezeda; Musralina, Lyazzat; Ghalichi, Ayshin; Penske, Sandra; Sabin, Susanna; Michel, Megan; Gretzinger, Joscha; A. Nelson, Elizabeth; Ferraz, Tiago; Nägele, Kathrin; Parker, Cody; Keller, Marcel; K. Guevara, Evelyn; Feldman, Michal; Eisenmann, Stefanie; Skourtanioti, Eirini; Giffin, Karen; Alberto Gnecchi-Ruscone, Guido; Friederich, Susanne; Schimmenti, Vittoria; Khartanovich, Valery; K. Karapetian, Marina; S. Chaplygin, Mikhail; V. Kufterin, Vladimir; A. Khokhlov, Aleksandr; A. Chizhevsky, Andrey; A. Stashenkov, Dmitry; F. Kochkina, Anna; Tejedor-Rodríguez, Cristina; García-Martínez de Lagrán, Íñigo; Arcusa-Magallón, Héctor; Garrido-Pena, Rafael; Ignacio Royo-Guillén, José; Nováček, Jan; Rottier, Stéphane; Kacki, Sacha; Saintot, Sylvie; Kaverzneva, Elena; B. Belinskiy, Andrej; Velemínský, Petr; Limburský, Petr; Kostka, Michal; Loe, Louise; Popescu, Elizabeth; Clarke, Rachel; Lyons, Alice; Mortimer, Richard; Sajantila, Antti; Chinique de Armas, Yadira; Teresita Hernandez Godoy, Silvia; I. Hernández-Zaragoza, Diana; Pearson, Jessica; Binder, Didier; Lefranc, Philippe; R. Kantorovich, Anatoly; E. Maslov, Vladimir; Lai, Luca; Zoledziewska, Magdalena; F. Beckett, Jessica; Langová, Michaela; Danielisová, Alžběta; Ingman, Tara; García Atiénzar, Gabriel; Paz de Miguel Ibáñez, Maria; Romero, Alejandro; Sperduti, Alessandra; Beckett, Sophie; J. Salter, Susannah; D. Zilivinskaya, Emma; V. Vasil’ev, Dmitry; von Heyking, Kristin; L. Burger, Richard; C. Salazar, Lucy; Amkreutz, Luc; Navruzbekov, Masnav; Rosenstock, Eva; Alonso-Fernández, Carmen; Slavchev, Vladimir; A. Kalmykov, Alexey; Ch. Atabiev, Biaslan; Batieva, Elena; Alvarez Calmet, Micaela; Llamas, Bastien; Schultz, Michael; Krauß, Raiko; Jiménez-Echevarría, Javier; Francken, Michael; Shnaider, Svetlana; de Knijff, Peter; Altena, Eveline; Van de Vijver, Katrien; Fehren-Schmitz, Lars; A. Tung, Tiffiny; Lösch, Sandra; Dobrovolskaya, Maria; Makarov, Nikolaj; Read, Chris; Van Twest, Melanie; Sagona, Claudia; C. Ramsl, Peter; Akar, Murat; Aslihan Yener, K.; Carmona Ballestero, Eduardo; Cucca, Francesco; Mazzarello, Vittorio; Utrilla, Pilar; Rademaker, Kurt; Fernández-Domínguez, Eva; Baird, Douglas; Semal, Patrick; Márquez-Morfín, Lourdes; Roksandic, Mirjana; Steiner, Hubert; Carlos Salazar-García, Domingo; Shishlina, Natalia; Selim Erdal, Yilmaz; Hallgren, Fredrik; Boyadzhiev, Yavor; Boyadzhiev, Kamen; Küßner, Mario; Sayer, Duncan; Onkamo, Päivi; Skeates, Robin; Rojo-Guerra, Manuel; Buzhilova, Alexandra; Khussainova, Elmira; B. Djansugurova, Leyla; Z. Beisenov, Arman; Samashev, Zainolla; Massy, Ken; Mannino, Marcello; Moiseyev, Vyacheslav; Mannermaa, Kristiina; Balanovsky, Oleg; Deguilloux, Marie-France; Reinhold, Sabine; Hansen, Svend; P. Kitov, Egor; Dobeš, Miroslav; Ernée, Michal; Meller, Harald; W. Alt, Kurt; Prüfer, Kay; Warinner, Christina; Schiffels, Stephan; W. Stockhammer, Philipp; Bos, Kirsten; Posth, Cosimo; Herbig, Alexander; Haak, Wolfgang; Krause, Johannes; Kühnert, Denise

doi:10.1126/science.abi5658

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Ten millennia of hepatitis B virus evolution

Shared by NobleBlocks on Oct 8, 2021 • 12:00 AM UTC

Authors:

Arthur Kocher

Luka Papac

Rodrigo Barquera

Abstract

Ancient DNA traces the history of hepatitis B Hepatitis B virus (HBV) infections represent a worldwide human health concern. To study the history of this pathogen, Kocher et al . identified 137 human remains with detectable levels of virus dating between 400 and 10,000 years ago. Sequencing and anal...

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