Comparative cellular analysis of motor cortex in human, marmoset and mouse

E. Bakken, Trygve; L. Jorstad, Nikolas; Hu, Qiwen; B. Lake, Blue; Tian, Wei; Kalmbach, Brian; Crow, Megan; D. Hodge, Rebecca; M. Krienen, Fenna; A. Sorensen, Staci; Eggermont, Jeroen; Yao, Zizhen; D. Aevermann, Brian; Aldridge, Andrew; Bartlett, Anna; Bertagnolli, Darren; Casper, Tamara; Castanon, Rosa; Crichton, Kirsten; L. Daigle, Tanya; Dalley, Rachel; Dee, Nick; Dembrow, Nikolai; Diep, Dinh; Ding, Song‐Lin; Dong, Weixiu; Fang, Rongxin; Fischer, Stephan; Goldman, Melissa; Goldy, Jeff; T. Graybuck, Lucas; R. Herb, Brian; Hou, Xiaomeng; Kancherla, Jayaram; Kroll, Matthew; Lathia, Kanan; van Lew, Baldur; Eric Li, Yang; S. Liu, Christine; Liu, Hanqing; Lucero, Jacinta; Mahurkar, Anup; McMillen, Delissa; A. Miller, Jeremy; R. Moussa, Marmar; R. Nery, Joseph; R. Nicovich, Philip; Niu, Sheng-Yong; Orvis, Joshua; Osteen, Julia; F. Owen, Scott; R. Palmer, Carter; Pham, Thanh; Plongthongkum, Nongluk; Poirion, Olivier; Reed, Nora; Rimorin, Christine; Rivkin, Angeline; J. Romanow, William; E. Sedeño-Cortés, Adriana; Siletti, Kimberly; Somasundaram, Saroja; Šulc, Josef; Tieu, Michael; Torkelson, Amy; Tung, Herman; Wang, Xinxin; Xie, Fangming; Marie Yanny, Anna; Zhang, Renee; A. Ament, Seth; Margarita Behrens, M.; Corrada Bravo, Héctor; Chun, Jerold; Dobin, Alexander; Gillis, Jesse; Hertzano, Ronna; R. Hof, Patrick; Höllt, Thomas; D. Horwitz, Gregory; Dirk Keene, C.; V. Kharchenko, Peter; L. Ko, Andrew; P. F. Lelieveldt, Boudewijn; Luo, Chongyuan; A. Mukamel, Eran; Pinto‐Duarte, António; Preißl, Sebastian; Regev, Aviv; Ren, Bing; H. Scheuermann, Richard; A. Smith, Kimberly; J. Spain, William; White, Owen; Koch, Christof; Hawrylycz, Michael; Tasic, Bosiljka; Z. Macosko, Evan; A. McCarroll, Steven; T. Ting, Jonathan; Zeng, Hongkui; Zhang, Kun; Feng, Guoping; R. Ecker, Joseph; Linnarsson, Sten; S. Lein, Ed

doi:10.1038/s41586-021-03465-8

Public

Comparative cellular analysis of motor cortex in human, marmoset and mouse

Published in Nature • Oct 6, 2021

Authors:

Trygve E. Bakken

Nikolas L. Jorstad

Qiwen Hu

Abstract

. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monkeys and mice, we demonstrate a broadly conserved cellular makeup of this region, with similarities that mirror evolutionary distance and are consistent between the transcr...

Subject

Biology

Marmoset

Transcriptome

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