Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study

Monel, Blandine; Planas, Delphine; Grzelak, Ludivine; Smith, Nikaïa; Robillard, Nicolas; Staropoli, Isabelle; Gonçalves, Pedro; Porrot, Françoise; Guivel‐Benhassine, Florence; Demory Guinet, Nathalie; Rodary, Julien; Puech, Julien; Euzen, Victor; Bélec, Laurent; Orvoën, Galdric; Nunes, Léa; Moulin, Véronique; Fourgeaud, Jacques; Wack, Maxime; Imbeaud, Sandrine; Campagne, Pascal; Duffy, Darragh; P. Di Santo, James; Bruel, Timothée; Péré, Hélène; Veyer, David; Schwartz, Olivier

doi:10.1016/j.ebiom.2021.103637

Public

Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study

Published in EBioMedicine • Oct 22, 2021

Authors:

Blandine Monel

Delphine Planas

Ludivine Grzelak

Abstract

BACKGROUND: The dynamics of SARS-CoV-2 alpha variant shedding and immune responses at the nasal mucosa remain poorly characterised. METHODS: We measured infectious viral release, antibodies and cytokines in 426 PCR+ nasopharyngeal swabs from individuals harboring non-alpha or alpha variants. FINDING...

Subject

Virology

Infectivity

Virus

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