The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

M Walker, Timothy; Miotto, Paolo; U. Köser, Claudio; W. Fowler, Philip; Knaggs, Jeff; Iqbal, Zamin; Hunt, Martin; Chindelevitch, Leonid; Farhat, Maha; María Cirillo, Daniela; Comas, Iñaki; E. Posey, James; Vally Omar, Shaheed; Peto, Tim; Suresh, Anita; Uplekar, Swapna; Laurent, Sacha; E. Colman, Rebecca; Nathanson, Carl‐Michael; Zignol, Matteo; Sarah Walker, Ann; W. Crook, Derrick; Ismail, Nazir; C. Rodwell, Timothy; Sarah Walker, A; J. C. Steyn, Adrie; Lalvani, Ajit; R. Baulard, Alain; Christoffels, Alan; Mendoza‐Ticona, Alberto; Trovato, Alberto; Skrahina, Alena; S. Lachapelle, Alexander; Brankin, Alice; S. Piatek, Amy; Gibertoni Cruz, Ana; Koch, Anastasia; Maurizio Cabibbe, Andrea; Spitaleri, Andrea; Pires Brandão, Angela; Chaiprasert, Angkana; Suresh, Anita; I. Barbova, A.; Van Rie, Annelies; Ghodousi, Arash; Bainomugisa, Arnold; Mandal, Ayan; Roohi, Aysha; Javid, Babak; Zhu, Baoli; Letcher, Brice; Rodrigues, Camilla; Nimmo, Camus; Nathanson, Carl‐Michael; Duncan, Carla; Coulter, Christopher; Utpatel, Christian; Liu, Chunfa; Grazian, Clara; Kong, Clare; U. Köser, Claudio; J. Wilson, Daniel; María Cirillo, Daniela; Matias, Daniela; Jorgensen, Danielle; Zimenkov, Danila; Chetty, Darren; Moore, David; A. Clifton, David; W. Crook, Derrick; van Soolingen, Dick; Liu, Dongxin; Kohlerschmidt, Donna; Barreira, Dráurio; Ngcamu, Dumisani; Santos-Lázaro, David; Kelly, Ellis; Borroni, Emanuele; Roycroft, Emma; André, Emmanuel; C. Böttger, Erik; Robinson, Esther; Menardo, Fabrizio; F Mendes, Flavia; Jamieson, Frances; Coll, Francesc; F. Gao, George; William Kasule, George; María Rossolini, Gian; Rodger, Gillian; Grace Smith, E.; Meintjes, Graeme; Thwaites, Guy; Hoffmann, Harald; Albert, Heidi; Cox, Helen; F. Laurenson, Ian; Comas, Iñaki; Arandjelović, Irena; Barilar, Ivan; Robledo, Jaime; Millard, James; C. Johnston, James; Posey, Jamie; R. Andrews, Jason; Knaggs, Jeff; L. Gardy, Jennifer; L. Guthrie, Jennifer; Taylor, Jill; Werngren, Jim; Metcalfe, John; Coronel, Jorge; Shea, Joseph; A. Carter, Joshua; MW Pinhata, Juliana; V. Kus, Julianne; Todt, Katharina; E. Holt, Kathryn; Nilgiriwala, Kayzad; Teixeira Ghisi, Kelen; M. Malone, Kerri; Faksri, Kiatichai; A. Musser, Kimberlee; Joseph, Lavania; Rigouts, Leen; Chindelevitch, Leonid; Jarrett, Lisa; Grandjean, Louis; Ferrazoli, Lucilaine; Rodrigues, Mabel; Farhat, Maha; Schito, Marco; Fitzgibbon, Margaret; Massinga Loembé, Marguerite; Wijkander, Maria; Ballif, Marie; Sylvianne Rabodoarivelo, Marie; Mihalic, Marina; H. Wilcox, Mark; Hunt, Martin; ZIGNOL, Matteo; Merker, Matthias; Egger, Matthias; R. O’Donnell, Max; Caws, Maxine; Wu, Mei-Hua; G. Whitfield, Michael; Inouye, Michael; Mansjö, Mikael; Ha Dang Thi, Minh; Joloba, Moses; M. Mostofa Kamal, S.; Okozi, Nana; ISMAIL, Nazir; Mistry, Nerges; N Hoang, Nhung; Rakotosamimanana, Niaina; I. Paton, Nicholas; M. V. Rancoita, Paola; Miotto, Paolo; Lapierre, Pascal; Hall, P.; Tang, Patrick; Claxton, Pauline; Wintringer, Penelope; M. Keller, Peter; Vuong Khac Thai, Phan; W. Fowler, Philip; Supply, Philip; Srilohasin, Prapaporn; Suriyaphol, Prapat; Rathod, Priti; Kambli, Priti; Groenheit, Ramona; E. Colman, Rebecca; Twee‐Hee Ong, Rick; M. Warren, Robin; J. Wilkinson, Robert; Diel, Roland; Siqueira de Oliveira, Rosângela; Khot, Rukhsar; Jou, Ruwen; Tahseen, Sabira; Laurent, Sacha; E. Gharbia, Saheer; Kouchaki, Samaneh; Shah, Sanchi; Plesnik, Sara; G. Earle, Sarah; J. Dunstan, Sarah; Hoosdally, Sarah; Mitarai, Satoshi; Gagneux, Sébastien; V Omar, Shaheed; Yao, Shen-Yuan; Grandjean Lapierre, Simon; Battaglia, Simone; Niemann, Stefan; Pandey, Sushil; Uplekar, Swapna; A. Halse, Tanya; Cohen, Ted; Cortes, Teresa; Prammananan, Therdsak; A. Kohl, Thomas; Thụy Thương Thương, Nguyễn; Ying Teo, Tik; Peto, Tim; C. Rodwell, Timothy; William, Timothy; M Walker, Timothy; R. Rogers, Thomas; Surve, Utkarsha; Mathys, Vanessa; Furió, Victoria; Cook, Victoria; Vijay, Srinivasan; Escuyer, Vincent; Dreyer, Viola; Sintchenko, Vitali; Saphonn, Vonthanak; Solano, Walter; Lin, Wan-Hsuan; Van Gemert, Wayne; He, Wencong; Yang, Yang; Zhao, Yanlin; Qin, Youwen; Xiao, Yu-Xin; Hasan, Zahra; Iqbal, Zamin; M. Puyén, Zully

doi:10.1016/s2666-5247(21)00301-3

Public

The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

Published in The Lancet Microbe • Mar 8, 2022

Authors:

Timothy M Walker

Paolo Miotto

Claudio U. Köser

Abstract

Background: complex (MTBC). We aimed to generate a WHO endorsed catalogue of mutations to serve as a global standard for interpreting molecular information for drug resistance prediction. Methods: A candidate gene approach was used to identify mutations as associated with resistance, or consistent w...

Subject

Ethambutol

Ethionamide

Mycobacterium tuberculosis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!