Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline

D. Santomasso, Bianca; J. Nastoupil, Loretta; Adkins, Sherry; Lacchetti, Christina; J. Schneider, Bryan; Anadkat, Milan; B. Atkins, Michael; J. Brassil, Kelly; M. Caterino, Jeffrey; Chau, Ian; J. Davies, Marianne; S. Ernstoff, Marc; Fecher, Leslie; Funchain, Pauline; Jaiyesimi, Ishmael; S. Mammen, Jennifer; Naidoo, Jarushka; Naing, Aung; Phillips, Tanyanika; D. Porter, Laura; A. Reichner, Cristina; Seigel, Carole; Song, Jung-Min; Spira, Alexander; Suarez-Almazor, Maria; Swami, Umang; A. Thompson, John; Vikas, Praveen; Wang, Yinghong; S. Weber, Jeffrey; Bollin, Kathryn; Ghosh, Monalisa

doi:10.1200/jco.21.01992

Public

Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline

Published in Journal of Clinical Oncology • Nov 1, 2021

Authors:

Bianca D. Santomasso

Loretta J. Nastoupil

Sherry Adkins

Abstract

PURPOSE: To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events (irAEs) in patients treated with chimeric antigen receptor (CAR) T-cell therapy. METHODS: A multidisciplinary panel of medical oncology, neurology, hematology, emerge...

Subject

Medicine

Cytokine release syndrome

Chimeric antigen receptor

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