AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

Váradi, Mihály; Anyango, Stephen; Deshpande, Mandar; Nair, Sreenath; Natassia, Cindy; Yordanova, Galabina; Yu Yuan, David; Stroe, Oana; Wood, Gemma; Laydon, Agata; Žídek, Augustin; Green, Tim; Tunyasuvunakool, Kathryn; Petersen, Stig; Jumper, John; Clancy, Ellen; Green, Richard; Vora, Ankur; Lutfi, Mira; Figurnov, Michael; Cowie, Andrew; Hobbs, Nicole; Kohli, Pushmeet; J. Kleywegt, Gerard; Birney, Ewan; Hassabis, Demis; Velankar, Sameer

doi:10.1093/nar/gkab1061

Public

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

Published in Nucleic Acids Research • Oct 19, 2021

Authors:

Mihály Váradi

Stephen Anyango

Mandar Deshpande

Abstract

The AlphaFold Protein Structure Database (AlphaFold DB, https://alphafold.ebi.ac.uk) is an openly accessible, extensive database of high-accuracy protein-structure predictions. Powered by AlphaFold v2.0 of DeepMind, it has enabled an unprecedented expansion of the structural coverage of the known pr...

Subject

Biology

Pairwise comparison

Sequence (biology)

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