The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies

Xu, Hongyang; Van Remmen, Holly

doi:10.1186/s13395-021-00280-7

Public

The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies

Published in Skeletal Muscle • Nov 12, 2021

Authors:

Hongyang Xu

Holly Van Remmen

Abstract

As a key regulator of cellular calcium homeostasis, the Sarcoendoplasmic Reticulum Calcium ATPase (SERCA) pump acts to transport calcium ions from the cytosol back to the sarcoplasmic reticulum (SR) following muscle contraction. SERCA function is closely associated with muscle health and function, a...

Subject

SERCA

Skeletal muscle

Calcium pump

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