Effect of High-Titer Convalescent Plasma on Progression to Severe Respiratory Failure or Death in Hospitalized Patients With COVID-19 Pneumonia: A Randomized Clinical Trial.

F, Menichetti; P, Popoli; M, Puopolo; Alegiani S, Spila; G, Tiseo; A, Bartoloni; Socio GV, De; S, Luchi; P, Blanc; M, Puoti; E, Toschi; M, Massari; L, Palmisano; G, Marano; M, Chiamenti; L, Martinelli; S, Franchi; C, Pallotto; LR, Suardi; Pasqua B, Luciani; M, Merli; P, Fabiani; L, Bertolucci; B, Borchi; S, Modica; S, Moneta; G, Marchetti; Monforte A, d'Arminio; L, Stoppini; N, Ferracchiato; S, Piconi; C, Fabbri; E, Beccastrini; R, Saccardi; A, Giacometti; S, Esperti; P, Pierotti; L, Bernini; C, Bianco; S, Benedetti; A, Lanzi; P, Bonfanti; M, Massari; S, Sani; A, Saracino; A, Castagna; L, Trabace; M, Lanza; D, Focosi; A, Mazzoni; M, Pistello; M, Falcone

doi:10.1001/jamanetworkopen.2021.36246

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Effect of High-Titer Convalescent Plasma on Progression to Severe Respiratory Failure or Death in Hospitalized Patients With COVID-19 Pneumonia: A Randomized Clinical Trial.

Shared by NobleBlocks on Nov 1, 2021 • 12:00 AM UTC

Authors:

Menichetti F

Popoli P

Puopolo M

Abstract

Importance Convalescent plasma (CP) has been generally unsuccessful in preventing worsening of respiratory failure or death in hospitalized patients with COVID-19 pneumonia.Objective To evaluate the efficacy of CP plus standard therapy (ST) vs ST alone in preventing worsening respiratory failure or ...

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