Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

Saito, Akatsuki; Irie, Takashi; Suzuki, Rigel; Maemura, Tadashi; Nasser, Hesham; Uriu, Keiya; Kosugi, Yusuke; Shirakawa, Kotaro; Sadamasu, Kenji; Kimura, Izumi; Ito, Jumpei; Wu, Jiaqi; Iwatsuki‐Horimoto, Kiyoko; Ito, Mutsumi; Yamayoshi, Seiya; Loeber, Samantha; Tsuda, Masumi; Wang, Lei; Ozono, Seiya; P. Butlertanaka, Erika; Tanaka, Yuri; Shimizu, Ryo; Shimizu, Kenta; Yoshimatsu, Kumiko; Kawabata, Ryoko; Sakaguchi, Takemasa; Tokunaga, Kenzo; Yoshida, Isao; Asakura, Hiroyuki; Nagashima, Mami; Kazuma, Yasuhiro; Nomura, Ryosuke; Horisawa, Yoshihito; Yoshimura, Kazuhisa; Takaori‐Kondo, Akifumi; Imai, Masaki; Chiba, Mika; Furihata, Hirotake; Hasebe, Haruyo; Kitazato, Kazuko; Kubo, Haruko; Misawa, Naoko; Morizako, Nanami; Noda, Kohei; Oide, Akiko; Suganami, Mai; Takahashi, Miyoko; Tsushima, Kana; Yokoyama, Miyabishara; Yuan, Yue; Tanaka, Shinya; Nakagawa, So; Ikeda, Terumasa; Fukuhara, Takasuke; Kawaoka, Yoshihiro; Sato, Kei

doi:10.1038/s41586-021-04266-9

Public

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

Published in Nature • Nov 25, 2021

Authors:

Akatsuki Saito

Takashi Irie

Rigel Suzuki

Abstract

Abstract During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, at the time of writing, four variants of concern are considered to be potentially hazardous to hu...

Subject

Pathogenicity

Mutation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

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