Perioperative ctDNA-Based Molecular Residual Disease Detection for Non–Small Cell Lung Cancer: A Prospective Multicenter Cohort Study (LUNGCA-1)

Xia, Liang; Mei, Jiandong; Kang, Ran; Deng, Senyi; Chen, Yaohui; Yang, Ying; Feng, Gang; Deng, Yulan; Gan, Fanyi; Lin, Yidan; Pu, Qiang; Ma, Lin; Lin, Feng; Yuan, Yong; Hu, Yang; Guo, Chenglin; Liao, Hu; Liu, Chengwu; Zhu, Yunke; Wang, Wenping; Liu, Zheng; Xu, Yuyang; Li, Kaidi; Li, Chuan; Li, Qingyun; He, Ji; Chen, Weizhi; Zhang, Xiaolong; Kou, Yingli; Wang, Yun; Wu, Zhu; Che, Guowei; Chen, Longqi; Liu, Lunxu

doi:10.1158/1078-0432.ccr-21-3044

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Perioperative ctDNA-Based Molecular Residual Disease Detection for Non–Small Cell Lung Cancer: A Prospective Multicenter Cohort Study (LUNGCA-1)

Shared by NobleBlocks on Nov 22, 2021 • 12:00 AM UTC

Authors:

Liang Xia

Jiandong Mei

Ran Kang

Abstract

Abstract Purpose: We assessed whether perioperative circulating tumor DNA (ctDNA) could be a biomarker for early detection of molecular residual disease (MRD) and prediction of postoperative relapse in resected non–small cell lung cancer (NSCLC). Experimental Design: Based on our prospective, multic...

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