Physiopathological Relevance of D-Serine in the Mammalian Cochlea

Wang, Jing; Serratrice, Nicolas; J. Lee, Cindy; François, Florence; V. Sweedler, Jonathan; Puel, Jean‐Luc; Mothet, Jean‐Pierre; Ruel, Jérôme

doi:10.3389/fncel.2021.733004

Public

Physiopathological Relevance of D-Serine in the Mammalian Cochlea

Published in Frontiers in Cellular Neuroscience • Dec 17, 2021

Authors:

Jing Wang

Nicolas Serratrice

Cindy J. Lee

Abstract

NMDA receptors (NMDARs) populate the complex between inner hair cell (IHC) and spiral ganglion neurons (SGNs) in the developing and mature cochlea. However, in the mature cochlea, activation of NMDARs is thought to mainly occur under pathological conditions such as excitotoxicity. Ototoxic drugs suc...

Subject

Spiral ganglion

Cochlea

NMDA receptor

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!