SerpinA3N attenuates ischemic stroke injury by reducing apoptosis and neuroinflammation

Zhang, Yu; Chen, Qianbo; Chen, Dashuang; Zhao, Wenqi; Wang, Hao‐Wei; Yang, Mei; Xiang, Zhenghua; Yuan, Hongbin

doi:10.1111/cns.13776

Public

SerpinA3N attenuates ischemic stroke injury by reducing apoptosis and neuroinflammation

Published in CNS Neuroscience & Therapeutics • Dec 12, 2021

Authors:

Yu Zhang

Qianbo Chen

Dashuang Chen

Abstract

OBJECTIVE: To assess the effect of serine protein inhibitor A3N (serpinA3N) in ischemic stroke and to explore its mechanism of action. METHODS: Mouse ischemic stroke model was induced by transient middle cerebral artery occlusion followed by reperfusion. The expression pattern of serpinA3N was asses...

Subject

Neuroinflammation

Stroke (engine)

Medicine

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