<scp>DBS</scp> of Thalamic Centromedian Nucleus for <scp>Lennox–Gastaut</scp> Syndrome (<scp>ESTEL</scp> Trial)

J. Dalic, Linda; E. L. Warren, Aaron; Bulluss, Kristian; Thevathasan, Wesley; Roten, Annie; Churilov, Leonid; S. Archer, John

doi:10.1002/ana.26280

Public

DBS of Thalamic Centromedian Nucleus for Lennox–Gastaut Syndrome (ESTEL Trial)

Published in Annals of Neurology • Dec 8, 2021

Authors:

Linda J. Dalic

Aaron E. L. Warren

Kristian Bulluss

Abstract

OBJECTIVE: Prior uncontrolled studies have reported seizure reductions following deep brain stimulation (DBS) in patients with Lennox-Gastaut syndrome (LGS), but evidence from randomized controlled studies is lacking. We aimed to formally assess the efficacy and safety of DBS to the centromedian tha...

Subject

Lennox–Gastaut syndrome

Randomized controlled trial

Anesthesia

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