Pan-cancer single-cell landscape of tumor-infiltrating T cells

Zheng, Liangtao; Qin, Shishang; Si, Wen; Wang, Anqiang; Xing, Baocai; Gao, Ranran; Ren, Xianwen; Wang, Li; Wu, Xiaojiang; Zhang, Ji; Wu, Nan; Zhang, Ning; Zheng, Hong; Ouyang, Hanqiang; Chen, Keyuan; Bu, Zhaode; Hu, Xueda; Ji, Jiafu; Zhang, Zemin

doi:10.1126/science.abe6474

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Pan-cancer single-cell landscape of tumor-infiltrating T cells

Published in Science • Dec 16, 2021

Authors:

Liangtao Zheng

Shishang Qin

Wen Si

Abstract

An atlas of cancer-associated T cells The tumor microenvironment contains many different kinds of immune cells, the composition, function, and roles of which are unclear. Using single-cell RNA sequencing of T cells in 21 cancer types from more than 300 patients, Zheng et al . identified differences ...

Subject

Biology

Tumor microenvironment

CD8

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