Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment

Q. Dinh, Huy; Pan, Feng; Wang, Geng; Huang, Qingfeng; Olingy, Claire; Wu, Zhi‐Yong; Wang, Shaohong; Xu, Xin; Xu, Xiu‐E; He, Jianzhong; Yang, Qian; Oršulić, Sandra; Haro, Marcela; Li, Liyan; Huang, Guowei; J. Breunig, Joshua; Phillip Koeffler, H.; C. Hedrick, Catherine; Xu, Li‐Yan; Lin, De‐Chen; Li, En‐Min

doi:10.1038/s41467-021-27599-5

Public

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment

Published in Nature Communications • Dec 17, 2021

Authors:

Huy Q. Dinh

Feng Pan

Geng Wang

Abstract

Abstract The tumor microenvironment is a highly complex ecosystem of diverse cell types, which shape cancer biology and impact the responsiveness to therapy. Here, we analyze the microenvironment of esophageal squamous cell carcinoma (ESCC) using single-cell transcriptome sequencing in 62,161 cells ...

Subject

Tumor microenvironment

Stromal cell

Biology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!