RNA sequencing of chronic GVHD skin lesions defines shared and unique inflammatory pathways characterizing lichen planus and morphea

Zouali, Habib; Lemasson, Juliette; Calugareanu, Andreea; Battail, Christophe; Michonneau, David; le Buanec, Hélène; Grolleau, Chloé; Cassius, Charles; Robin, Marie; Merandet, Marine; Dobos, Gabor; Mahevas, Thibault; Rybojad, Michel; de Masson, Adèle; Amode, Reyhan; Boland, Anne; Michel, Laurence; Sicre de Fontbrune, Flore; Peffault de Latour, Régis; Bruneval, Patrick; Ait-Oufella, Hafid; Battistella, Maxime; Jachiet, Marie; Bagot, Martine; Deleuze, Jean-François; Socié, Gérard; Bouaziz, Jean-David

doi:10.1182/bloodadvances.2021004707

Public

RNA sequencing of chronic GVHD skin lesions defines shared and unique inflammatory pathways characterizing lichen planus and morphea

Published in Blood Advances • Jan 10, 2022

Authors:

Habib Zouali

Juliette Lemasson

Andreea Calugareanu

Abstract

Cutaneous involvement of chronic graft-versus-host disease (cGVHD) has a wide range of manifestations including a lichenoid form with a currently assumed mixed Th1/Th17 signature and a sclerotic form with Th1 signature. Despite substantial heterogeneity of innate and adaptive immune cells recruited ...

Subject

Transcriptome

Biology

Immunology

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