Multiple early factors anticipate post-acute COVID-19 sequelae

Su, Yapeng; Yuan, Dan; Chen, Daniel; H. Ng, Rachel; Wang, Kai; Choi, Jongchan; Li, Sarah; Hong, Sunga; Zhang, Rongyu; Xie, Jingyi; A. Kornilov, Sergey; Scherler, Kelsey; Jimena Pavlovitch-Bedzyk, Ana; Dong, Shen; Lausted, Christopher; Lee, Inyoul; Fallen, Shannon; L. Dai, Chengzhen; Baloni, Priyanka; Smith, Brett; R. Duvvuri, Venkata; G. Anderson, Kristin; Li, Jing; Yang, Fan; J. Duncombe, Caroline; J. McCulloch, Denise; Rostomily, Clifford; Troisch, Pamela; Zhou, Jing; Mackay, Sean; DeGottardi, Quinn; May, Damon; Taniguchi, Ruth; Gittelman, Rachel; Klinger, Mark; M. Snyder, Thomas; Roper, Ryan; Wojciechowska, Gladys; M. Murray, Kim; Edmark, Rick; Evans, Simon; Jones, Lesley; Zhou, Yong; Rowen, Lee; Liu, Rachel; Chour, William; A. Algren, Heather; R. Berrington, William; A. Wallick, Julie; A. Cochran, Rebecca; Micikas, Mary; Wrin, Terri; J. Petropoulos, Christos; Cole, Hunter; Fischer, Trevan; Wei, Wei; S.�B. Hoon, Dave; D. Price, Nathan; Subramanian, Naeha; A. Hill, Joshua; Hadlock, Jennifer; T. Magis, Andrew; Ribas, Antoni; L. Lanier, Lewis; D. Boyd, Scott; A. Bluestone, Jeffrey; Y. Chu, Helen; Hood, Leroy; Gottardo, Raphaël; D. Greenberg, Philip; M. Davis, Mark; D. Goldman, Jason; R. Heath, James

doi:10.1016/j.cell.2022.01.014

Public

Multiple early factors anticipate post-acute COVID-19 sequelae

Published in Cell • Jan 25, 2022

Authors:

Yapeng Su

Dan Yuan

Daniel Chen

Abstract

Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2...

Subject

Convalescence

Biology

Coronavirus disease 2019 (COVID-19)

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