First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma: 3-year outcomes from CheckMate 743

Peters, Solange; Scherpereel, Arnaud; Cornelissen, Robin; Oulkhouir, Youssef; Greillier, Laurent; Ma, Kaplan; Talbot, Thomas; Monnet, I.; Hiret, Sandrine; Baas, P.; K. Nowak, Anna; Fujimoto, Nobukazu; S. Tsao, Anne; S. Mansfield, Aaron; Popat, Sanjay; Zhang, X.; Hu, Nan; Balli, David; Spires, Thomas; Zalcman, Gérard

doi:10.1016/j.annonc.2022.01.074

Public

First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma: 3-year outcomes from CheckMate 743

Published in Annals of Oncology • Feb 3, 2022

Authors:

Solange Peters

Arnaud Scherpereel

Robin Cornelissen

Abstract

•With a ≥3-year follow-up in CheckMate 743, nivolumab + ipilimumab continued to provide long-term OS benefit in first-line MPM.•Clinical benefits remained consistent across patient subgroups, including epithelioid versus non-epithelioid histology.•Discontinuing nivolumab + ipilimumab due to TRAEs di...

Subject

Medicine

Nivolumab

Ipilimumab

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