Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

Pervjakova, Natalia; Moen, Gunn-Helen; Carolina Borges, Maria; Ferreira, Teresa; P. Cook, James; Allard, Catherine; N. Beaumont, Robin; Canouil, Mickaël; Hatem, Gad; Heiskala, Anni; Joensuu, Anni; Karhunen, Ville; Heon Kwak, Soo; T. J. Lin, Frederick; Liu, Jun; L. Rifas‐Shiman, Sheryl; H.T. Tam, Claudia; Hung Tam, Wing; Þorleifsson, Guðmar; Andrew, Toby; Auvinen, Juha; Bhowmik, Bishwajit; Bonnefond, Amélie; Delahaye, Fabien; Demirkan, Ayşe; Froguel, Philippe; Haller‐Kikkatalo, Kadri; Harðardóttir, Hildur; Hummel, Sandra; Hussain, Akhtar; Kajantie, Eero; Keikkala, Elina; Khamis, Amna; Lahti, Jari; Lekva, Tove; Mustaniemi, Sanna; Sommer, Christine; Tagoma, Aili; Tzala, Evangelia; Uibo, Raivo; Vääräsmäki, Marja; Villa, Pia; I. Birkeland, Kåre; Bouchard, Luigi; M. van Duijn, Cornelia; Finer, Sarah; Groop, Leif; Hämäläinen, Esa; Hayes, Geoffrey; A. Hitman, G.; Chul Jang, Hak; Järvelin, Marjo‐Riitta; Karen Jenum, Anne; Laivuori, Hannele; C.W., Ronald; Melander, Olle; Oken, Emily; Soo Park, Kyong; Perron, Patrice; B. Prasad, Rashmi; Qvigstad, Elisabeth; Sebért, Sylvain; Stefánsson, Kāri; Steinthórsdóttir, Valgerður; Tuomi, Tiinamaija; Hivert, Marie‐France; W. Franks, Paul; I. McCarthy, Mark; M. Lindgren, Cecilia; M. Freathy, Rachel; A Lawlor, Deborah; P. Morris, Andrew; Mägi, Reedik

doi:10.1093/hmg/ddac050

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Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

Published in Human Molecular Genetics • Feb 25, 2022

Authors:

Natalia Pervjakova

Gunn-Helen Moen

Maria Carolina Borges

Abstract

Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and adverse perinatal outcomes. GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 diabetes (T2D). To improve our understanding of the aetiological factors and mol...

Subject

Gestational diabetes

Genome-wide association study

Biology

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