Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.

Pervjakova, Natalia; Moen, Gunn-Helen; Borges, Maria-Carolina; Ferreira, Teresa; P Cook, James; Allard, Catherine; N Beaumont, Robin; Canouil, Mickaël; Hatem, Gad; Heiskala, Anni; Joensuu, Anni; Karhunen, Ville; Heon Kwak, Soo; T J Lin, Frederick; Liu, Jun; Rifas-Shiman, Sheryl; H Tam, Claudia; Hung Tam, Wing; Thorleifsson, Gudmar; Andrew, Toby; Auvinen, Juha; Bhowmik, Bishwajit; Bonnefond, Amélie; Delahaye, Fabien; Demirkan, Ayse; Froguel, Philippe; Haller-Kikkatalo, Kadri; Hardardottir, Hildur; Hummel, Sandra; Hussain, Akhtar; Kajantie, Eero; Keikkala, Elina; Khamis, Amna; Lahti, Jari; Lekva, Tove; Mustaniemi, Sanna; Sommer, Christine; Tagoma, Aili; Tzala, Evangelia; Uibo, Raivo; Vääräsmäki, Marja; M Villa, Pia; I Birkeland, Kåre; Bouchard, Luigi; M Duijn, Cornelia; Finer, Sarah; Groop, Leif; Hämäläinen, Esa; M Hayes, Geoffrey; A Hitman, Graham

doi:10.1093/hmg/ddac050

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Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.

Published in Human molecular genetics • Sep 29, 2022

NobleIDark:/48914/w1/20260526/ED84D7F7Record on NobleID

Authors:

Natalia Pervjakova

,

Gunn-Helen Moen

,

Maria-Carolina Borges

Abstract

Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and adverse perinatal outcomes. GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 diabetes (T2D). To improve our understanding of the aetiological factors and mol...

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