Oxidative Stress and Assisted Reproduction: A Comprehensive Review of Its Pathophysiological Role and Strategies for Optimizing Embryo Culture Environment

Agarwal, Ashok; Maldonado Rosas, Israel; Anagnostopoulou, Christina; Cannarella, Rossella; Boitrelle, Florence; Villar, Lina; Finelli, Renata; Durairajanayagam, Damayanthi; Henkel, Ralf; Saleh, Ramadan

doi:10.3390/antiox11030477

Public

Oxidative Stress and Assisted Reproduction: A Comprehensive Review of Its Pathophysiological Role and Strategies for Optimizing Embryo Culture Environment

Published in Antioxidants • Feb 28, 2022

Authors:

Ashok Agarwal

Israel Maldonado Rosas

Christina Anagnostopoulou

Abstract

Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and antioxidants has been established as an important factor that can negatively affect the outcomes of assisted reproductive techniques (ARTs). Excess ROS exert their pathological effects through damage to cellular lipi...

Subject

Blastocyst

Cell biology

Oxidative stress

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