Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

Chen, Qi; Liang, Xi; Wu, Tianzhou; Jiang, Jing; Jiang, Yongpo; Zhang, Sheng; Ruan, Yanyun; Zhang, Huaping; Zhang, Chao; Chen, Peng; Lv, Yuhang; Xin, Jiaojiao; Shi, Dongyan; Chen, Xin; Li­, ­Jun; Xu, Yinghe

doi:10.1186/s12967-022-03320-y

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Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

Published in Journal of Translational Medicine • Mar 14, 2022

Authors:

Qi Chen

Xi Liang

Tianzhou Wu

Abstract

BACKGROUND: Sepsis is defined as a systemic inflammatory response to microbial infections with multiple organ dysfunction. This study analysed untargeted metabolomics combined with proteomics of serum from patients with sepsis to reveal the underlying pathological mechanisms involved in sepsis. METH...

Subject

Sepsis

Metabolomics

Metabolome

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