Safety and Feasibility of Research Lumbar Puncture in Huntington's Disease: The HDClarity Cohort and Bioresource.

FB, Rodrigues; G, Owen; S, Sathe; E, Pak; D, Kaur; AG, Ehrhardt; S, Lifer; J, Townhill; K, Schubert; BR, Leavitt; M, Guttman; J, Bang; J, Lewerenz; J, Levey; C, Sampaio; EJ, Wild

doi:10.3233/jhd-210508

Public

Safety and Feasibility of Research Lumbar Puncture in Huntington's Disease: The HDClarity Cohort and Bioresource.

Shared by NobleBlocks on Jan 1, 2022 • 12:00 AM UTC

Authors:

Rodrigues FB

Owen G

Sathe S

Abstract

Background Biomarkers are needed to monitor disease progression, target engagement and efficacy in Huntington's disease (HD). Cerebrospinal fluid (CSF) is an ideal medium to research such biomarkers due to its proximity to the brain.Objective To investigate the safety and feasibility of research lum...

Subject

Blood

Cerebrospinal fluid

Biomarkers

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