Safety and Feasibility of Research Lumbar Puncture in Huntington’s Disease: The HDClarity Cohort and Bioresource

B. Rodrigues, Filipe; the HDClarity Investigators, for; Owen, Gail; Sathe, Swati; Pak, Elena; Kaur, Dipinder; G. Ehrhardt, Anka; Lifer, Sherry; Townhill, Jenny; Schubert, Katarzyna; R. Leavitt, Blair; Guttman, Mark; Bang, Jee; Lewerenz, Jan; Levey, Jamie; Sampaio, Cristina; J. Wild, Edward

doi:10.3233/jhd-210508

Public

Safety and Feasibility of Research Lumbar Puncture in Huntington’s Disease: The HDClarity Cohort and Bioresource

Published in Journal of Huntington s Disease • Mar 1, 2022

Authors:

Filipe B. Rodrigues

for the HDClarity Investigators

Gail Owen

Abstract

BACKGROUND: Biomarkers are needed to monitor disease progression, target engagement and efficacy in Huntington's disease (HD). Cerebrospinal fluid (CSF) is an ideal medium to research such biomarkers due to its proximity to the brain. OBJECTIVE: To investigate the safety and feasibility of research ...

Subject

Medicine

Cohort

Lumbar puncture

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!