Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases

El-Arif, George; Khazaal, Shaymaa; Farhat, Antonella; Harb, Julien; Annweiler, Cédric; Wu, Yingliang; Cao, Zhijian; Kovacic, Hervé; Abi Khattar, Ziad; Fajloun, Ziad; Sabatier, Jean‐Marc

doi:10.3390/molecules27072048

Public

Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases

Published in Molecules • Mar 22, 2022

Authors:

George El-Arif

Shaymaa Khazaal

Antonella Farhat

Abstract

The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein to its cellular receptor, the angiotensin-converting enzyme 2 (ACE2), causes its downregulation, which subsequently leads to the dysregulation of the renin-angiotensin system (RAS) in favor of the ACE-...

Subject

Coronavirus disease 2019 (COVID-19)

Angiotensin II

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!