Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study

Yu-hin Chan, Eugene; L.M. Yu, Ellen; Angeletti, Andrea; Arslan, Zainab; Basu, Biswanath; Boyer, Olivia; Chan, Chang-Yien; Colucci, Manuela; Dorval, Guillaume; Dossier, Claire; Drovandi, Stefania; Marco Ghiggeri, Gian; S. Gipson, Debbie; Hamada, Riku; Hogan, Julien; Ishikura, Kenji; Kamei, Koichi; J. Kemper, Markus; Lap-tak Ma, Alison; S. Parekh, Rulan; Radhakrishnan, Seetha; Saini, Priya; Shen, Qian; Sinha, Rajiv; Subun, Chantida; Teo, Sharon; Vivarelli, Marina; Webb, Hazel; Xu, Hong; Kim Yap, Hui; Tullus, Kjell

doi:10.1681/asn.2021111472

Public

Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study

Published in Journal of the American Society of Nephrology • Mar 30, 2022

Authors:

Eugene Yu-hin Chan

Ellen L.M. Yu

Andrea Angeletti

Abstract

Significance Statement Children with frequently relapsing, steroid-dependent nephrotic syndrome (FRSDNS) often require multiple courses of rituximab. However, long-term effects from repeated treatments remain unknown. In this international, multicenter study of 346 children receiving 1149 courses of...

Subject

Rituximab

Medicine

Idiopathic Nephrotic Syndrome

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