Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections

Terreri, Sara; Piano Mortari, Eva; Vinci, M.; Russo, Cristina; Alteri, Claudia; Albano, Christian; Colavita, Francesca; Gramigna, Giulia; Agrati, Chiara; Linardos, Giulia; Coltella, Luana; Colagrossi, Luna; Deriu, G.P.; Luisa Ciofi degli Atti, Marta; Rizzo, Caterina; Scarsella, Marco; Brugaletta, Rita; Camisa, Vincenzo; Santoro, Annapaola; Roscilli, Giuseppe; Pavoni, Emiliano; Muzi, Alessia; Magnavita, Nicola; Scutari, Rossana; Villani, Alberto; Raponi, Massimiliano; Locatelli, Franco; Federico Perno, Carlo; Zaffina, Salvatore; Carsetti, Rita

doi:10.1016/j.chom.2022.01.003

Public

Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections

Published in Cell Host & Microbe • Jan 25, 2022

Authors:

Sara Terreri

Eva Piano Mortari

M. Vinci

Abstract

Breakthrough SARS-CoV-2 infections in fully vaccinated individuals are considered a consequence of waning immunity. Serum antibodies represent the most measurable outcome of vaccine-induced B cell memory. When antibodies decline, memory B cells are expected to persist and perform their function, pre...

Subject

Memory B cell

Antibody

Immunization

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