Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19

Florescu, Simin; Stanciu, Delia; Zaharia, Mihaela; Kosa, Alma; Codreanu, Daniel; Kidwai, Aneela; Masood, Sobia; Kaye, Callum; Coutts, Amanda; MacKay, Lynn; Summers, Charlotte; Polgarova, Petra; Farahi, Neda; Fox, Eleonore; McWilliam, Stephen; B. Hawcutt, Daniel; Rad, Laura; O’Malley, Laura; Whitbread, Jennifer; Jones, Dawn; Dore, Rachael; Saunderson, Paula; Kelsall, Olivia; Cowley, Nicholas; Wild, Laura; Thrush, Jessica; Wood, Hannah; Austin, Karen; Bélteczki, János; Magyar, István; Fazekas, Ágnes; Kovács, Sándor; Szőke, Viktória; Donnelly, Adrian; Kelly, Martin; Smyth, Naoise; O’Kane, Sinéad; McClintock, Declan; Warnock, Majella; Campbell, Ryan; McCallion, Edmund; Azaiz, Amine; Charron, Cyril; Godement, Mathieu; Géri, Guillaume; Vieillard-Baron, Antoine; Johnson, Paul; McKenna, Shirley; Hanley, Joanne; Currie, Andrew; Allen, Barbara; McGoldrick, Clare; McMaster, Moyra; Mani, Ashwin; Mathew, Meghena; Kandeepan, Revathi; Vignesh, C; TV, Bharath; Ramakrishnan, N; James, Augustian; Elvira, Evangeline; Jayakumar, Devachandran; Ramachandran, Pratheema; Babu, Suresh; Ebenezer, R; Krishnaoorthy, S; Ranganathan, Lakshmi; Ganesan, Manisha; Shree, Madhu; Guilder, Eileen; Butler, Magdalena; Cowdrey, Keri-Anne; Robertson, Melissa; Ali, Farisha; McMahon, Ellie; Duffy, Eamon; Chen, Yan; Simmonds, Catherine; McConnochie, Rachael; O’Connor, Caroline; El-Khawas, Khaled; Richardson, Angus; Hill, Dianne; J. 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doi:10.1001/jama.2022.2910

Public

Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19

Published in JAMA • Mar 22, 2022

Authors:

Simin Florescu

Delia Stanciu

Mihaela Zaharia

Abstract

Importance: The efficacy of antiplatelet therapy in critically ill patients with COVID-19 is uncertain. Objective: To determine whether antiplatelet therapy improves outcomes for critically ill adults with COVID-19. Design, Setting, and Participants: In an ongoing adaptive platform trial (REMAP-CAP)...

Subject

Medicine

Intensive care unit

Critically ill

Research Assistant

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