Effectiveness of mRNA Vaccination in Preventing COVID-19–Associated Invasive Mechanical Ventilation and Death — United States, March 2021–January 2022

W. Tenforde, Mark; H. Self, Wesley; Gaglani, Manjusha; A. Ginde, Adit; J. Douin, David; Keipp Talbot, H.; D. Casey, Jonathan; M. Mohr, Nicholas; Zepeski, Anne; McNeal, Tresa; Ghamande, Shekhar; W. Gibbs, Kevin; Clark Files, D.; N. Hager, David; Shehu, Arber; E. Prekker, Matthew; Frosch, Anne; N. Gong, Michelle; Mohamed, Amira; J. Johnson, Nicholas; Srinivasan, Vasisht; S. Steingrub, Jay; D. Peltan, Ithan; M. Brown, Samuel; T. Martin, Emily; S. Monto, Arnold; Khan, Akram; L. Hough, Catherine; W. Busse, Laurence; Duggal, Abhijit; G. Wilson, Jennifer; Qadir, Nida; Y. Chang, Steven; Mallow, Christopher; Rivas, Carolina; M. Babcock, Hilary; H. Kwon, Jennie; C. Exline, Matthew; Botros, Mena; S. Lauring, Adam; I. Shapiro, Nathan; Halasa, Natasha; D. Chappell, James; G. Grijalva, Carlos; W. Rice, Todd; D. Jones, Ian; B. Stubblefield, William; Baughman, Adrienne; N. Womack, Kelsey; P. Rhoads, Jillian; J. Lindsell, Christopher; W. Hart, Kimberly; Zhu, Yuwei; Adams, Katherine; Surie, Diya; McMorrow, Meredith; M. Patel, Manish; Network, IVY

doi:10.15585/mmwr.mm7112e1

Public

Effectiveness of mRNA Vaccination in Preventing COVID-19–Associated Invasive Mechanical Ventilation and Death — United States, March 2021–January 2022

Published in MMWR Morbidity and Mortality Weekly Report • Mar 18, 2022

Authors:

Mark W. Tenforde

Wesley H. Self

Manjusha Gaglani

Abstract

COVID-19 mRNA vaccines (BNT162b2 [Pfizer-BioNTech] and mRNA-1273 [Moderna]) are effective at preventing COVID-19-associated hospitalization (1-3). However, how well mRNA vaccines protect against the most severe outcomes of these hospitalizations, including invasive mechanical ventilation (IMV) or de...

Subject

Medicine

Vaccination

Mechanical ventilation

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