A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV

Ndlangisa, Kedibone; du Plessis, Mignon; W. Lo, Stephanie; de Gouveia, Linda; Chaguza, Chrispin; Antonio, Martín; Kwambana-Adams, Brenda; Cornick, Jennifer; Everett, Dean; Dagan, Ron; A. Hawkins, Paulina; Beall, Bernard; Corso, Alejandra; Cristine Grassi Almeida, Samanta; J. Ochoa, Theresa; Obaro, Stephen; Shakoor, Sadia; S. Donkor, Eric; A. Gladstone, Rebecca; Ho, Pak‐Leung; Paragi, Metka; Doiphode, Sanjay; Srifuengfung, Somporn; Ford, Rebecca; C. Moïsi, Jennifer; K. Saha, Samir; Bigogo, Godfrey; Sigaúque, Betuel; Köseoğlu Eser, Özgen; Elmdaghri, Naima; Titov, Leonid; Turner, Paul; L. Ravi Kumar, K.; Kandasamy, Rama; Ea, Egorova; Ip, Margaret; F. Breiman, Robert; P. Klugman, Keith; McGee, Lesley; D. Bentley, Stephen; von Gottberg, Anne

doi:10.1099/mgen.0.000746

Public

A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV

Published in Microbial Genomics • Apr 6, 2022

Authors:

Kedibone Ndlangisa

Mignon du Plessis

Stephanie W. Lo

Abstract

Pneumococcal serotype 35B is an important non-conjugate vaccine (non-PCV) serotype. Its continued emergence, post-PCV7 in the USA, was associated with expansion of a pre-existing 35B clone (clonal complex [CC] 558) along with post-PCV13 emergence of a non-35B clone previously associated with PCV ser...

Subject

Serotype

Biology

Streptococcus pneumoniae

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