A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation

Wolf, Martin; Poupardin, Rodolphe; Ebner‐Peking, Patricia; Cronemberger Andrade, André; Blöchl, Constantin; Obermayer, Astrid; Gueths Gomes, Fausto; Vári, Balázs; Maeding, Nicole; Eminger, Essi; Binder, Heide‐Marie; M. Raninger, Anna; Hochmann, Sarah; Brachtl, Gabriele; Spittler, Andreas; Heuser, Thomas; Ofir, Racheli; G. Huber, Christian; Aberman, Zami; Schallmoser, Katharina; Volk, Hans‐Dieter; Strunk, Dirk

doi:10.1002/jev2.12207

Public

A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation

Published in Journal of Extracellular Vesicles • Apr 1, 2022

Authors:

Martin Wolf

Rodolphe Poupardin

Patricia Ebner‐Peking

Abstract

Nanoparticles can acquire a plasma protein corona defining their biological identity. Corona functions were previously considered for cell-derived extracellular vesicles (EVs). Here we demonstrate that nano-sized EVs from therapy-grade human placental-expanded (PLX) stromal cells are surrounded by a...

Subject

Angiogenesis

Cell biology

Chemistry

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