High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Xia, Jingen; Gu, Sichao; Lei, Wei; Zhang, Jihua; Wei, Hui; Liu, Chao; Zhang, Han; Lu, Rongli; Zhang, Liqiong; Jiang, Mingyan; Hu, Chao; Cheng, Zhenshun; Wei, Chaojie; Chen, Yusheng; Lu, Fengfeng; Chen, Min; Bi, Hong; Liu, Hui; Yan, Cunzi; Teng, Hong; Yang, Yang; Chen, Liang; Ge, Yanlei; Hou, Pengguo; Liu, Jialin; Gao, Weiwei; Zhang, Yi; Feng, Yingying; Tao, Cheng; Huang, Xu; Pan, Pinhua; Luo, Hong; Yun, Chunmei; Zhan, Qingyuan

doi:10.1186/s13054-022-03973-7

Public

High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Published in Critical Care • Apr 15, 2022

Authors:

Jingen Xia

Sichao Gu

Wei Lei

Abstract

BACKGROUND: High-flow nasal cannula (HFNC) can improve ventilatory function in patients with acute COPD exacerbation. However, its effect on clinical outcomes remains uncertain. METHODS: This randomized controlled trial was conducted from July 2017 to December 2020 in 16 tertiary hospitals in China....

Subject

Medicine

Interquartile range

Nasal cannula

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