Deep Submucosal Invasion Is Not an Independent Risk Factor for Lymph Node Metastasis in T1 Colorectal Cancer: A Meta-Analysis

W. Zwager, Liselotte; A.J. Bastiaansen, Barbara; S.M. Montazeri, Nahid; Hompes, Roel; Barresi, Valeria; Ichimasa, Katsuro; Kawachi, Hiroshi; Machado, Isidro; Masaki, Tadahiko; Sheng, Weiqi; Tanaka, Shinji; Togashi, Kazutomo; Yasue, Chihiro; Fockens, Paul; M.G. Moons, Leon; Dekker, Evelien

doi:10.1053/j.gastro.2022.04.010

Public

Deep Submucosal Invasion Is Not an Independent Risk Factor for Lymph Node Metastasis in T1 Colorectal Cancer: A Meta-Analysis

Published in Gastroenterology • Apr 15, 2022

Authors:

Liselotte W. Zwager

Barbara A.J. Bastiaansen

Nahid S.M. Montazeri

Abstract

BACKGROUND & AIMS: Deep submucosal invasion (DSI) is considered a key risk factor for lymph node metastasis (LNM) and important criterion to recommend surgery in T1 colorectal cancer. However, metastatic risk for DSI is shown to be low in the absence of other histologic risk factors. This meta-analy...

Subject

Lymphovascular invasion

Medicine

Tumor budding

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