Perfusate Metabolomics Content and Expression of Tubular Transporters During Human Kidney Graft Preservation by Hypothermic Machine Perfusion

Faucher, Quentin; Alarcan, Hugo; Sauvage, François‐Ludovic; Forestier, Lionel; Miquelestorena‐Standley, Elodie; Nadal‐Desbarats, Lydie; Arnion, Hélène; Venhard, Jean‐Christophe; Brichart, N.; Bruyère, F.; Marquet, Pierre; Barin‐Le Guellec, Chantal

doi:10.1097/tp.0000000000004129

Public

Perfusate Metabolomics Content and Expression of Tubular Transporters During Human Kidney Graft Preservation by Hypothermic Machine Perfusion

Published in Transplantation • Apr 20, 2022

Authors:

Quentin Faucher

Hugo Alarcan

François‐Ludovic Sauvage

Abstract

BACKGROUND: Ischemia-related injury during the preimplantation period impacts kidney graft outcome. Evaluating these lesions by a noninvasive approach before transplantation could help us to understand graft injury mechanisms and identify potential biomarkers predictive of graft outcomes. This study...

Subject

Metabolomics

Perfusion

Machine perfusion

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