Nanobody-based CAR-T cells for cancer immunotherapy

Safarzadeh Kozani, Pouya; Naseri, Abdolhossein; Mohamad Javad Mirarefin, Seyed; Salem, Faeze; Nikbakht, Mojtaba; Evazi Bakhshi, Sahar; Safarzadeh Kozani, Pooria

doi:10.1186/s40364-022-00371-7

Public

Nanobody-based CAR-T cells for cancer immunotherapy

Published in Biomarker Research • Apr 25, 2022

Authors:

Pouya Safarzadeh Kozani

Abdolhossein Naseri

Seyed Mohamad Javad Mirarefin

Abstract

Chimeric antigen receptor T-cell (CAR-T) therapy is the result of combining genetic engineering-based cancer immunotherapy with adoptive cell therapy (ACT). CAR-T therapy has been successful in treating various types of hematological cancers. CARs are receptors made of an extracellular domain, a mem...

Subject

Chimeric antigen receptor

Monoclonal antibody

Antigen

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!