IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making.

Xiaoqing, Chang,; Yu-Mei, Tan,; David G, Allen,; Shannon, Bell,; Paul C, Brown,; Lauren, Browning,; Patricia, Ceger,; Jeffery, Gearhart,; Pertti J, Hakkinen,; Shruti V, Kabadi,; Nicole C, Kleinstreuer,; Annie, Lumen,; Joanna, Matheson,; Alicia, Paini,; Heather A, Pangburn,; Elijah J, Petersen,; Emily N, Reinke,; Alexandre J S, Ribeiro,; Nisha, Sipes,; Lisa M, Sweeney,; John F, Wambaugh,; Ronald, Wange,; Barbara A, Wetmore,; Moiz, Mumtaz,

doi:10.3390/toxics10050232

Public

IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making.

Published in Toxics • May 1, 2022

Authors:

Chang, Xiaoqing

Tan, Yu-Mei

Allen, David G

Abstract

During the past few decades, the science of toxicology has been undergoing a transformation from observational to predictive science. New approach methodologies (NAMs), including in vitro assays, in silico models, read-across, and in vitro to in vivo extrapolation (IVIVE), are being developed to red...

Subject

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

absorption

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