Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

Soomro, Mehreen; A. Stadler, Michael; Dand, Nick; Bluett, James; R. Jadon, Deepak; Jalalinajafabadi, Farideh; Duckworth, Michael; Ho, Pauline; Marzo‐Ortega, Helena; Helliwell, Philip; W. Ryan, Anthony; Kane, David; Korendowych, Eleanor; A. Simpson, Michael; Packham, Jon; McManus, Ross; Gabay, Cem; Lamacchia, Céline; J. Nissen, Michael; A. Brown, Matthew; Verstappen, Suzanne; van Staa, Tjeerd; N. Barker, Jonathan; Smith, Catherine; BADBIR Study Group, the; BSTOP study group, the; FitzGerald, Oliver; McHugh, Neil; B. Warren, Richard; Bowes, John; Barton, Anne

doi:10.1002/art.42154

Public

Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

Published in Arthritis & Rheumatology • May 4, 2022

Authors:

Mehreen Soomro

Michael A. Stadler

Nick Dand

Abstract

Objectives Psoriatic arthritis (PsA) has a strong genetic component, and the identification of genetic risk factors could help identify the ~30% of psoriasis patients at high risk of developing PsA. Our objectives were to identify genetic risk factors and pathways that differentiate PsA from cutaneo...

Subject

Medicine

Genome-wide association study

Heritability

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