Quantification of amyloid PET for future clinical use: a state-of-the-art review

Pemberton, Hugh; E. Collij, Lyduine; Heeman, Fiona; Bollack, Ariane; Shekari, Mahnaz; Salvadó, Gemma; Lopes Alves, Isadora; Vállez García, David; Battle, Mark; Buckley, Christopher; Stephens, Andrew; Bullich, Santiago; Garibotto, Valentina; Barkhof, Frederik; Domingo Gispert, Juan; Farrar, Gill

doi:10.1007/s00259-022-05784-y

Public

Quantification of amyloid PET for future clinical use: a state-of-the-art review

Published in European Journal of Nuclear Medicine and Molecular Imaging • Apr 7, 2022

Authors:

Hugh Pemberton

Lyduine E. Collij

Fiona Heeman

Abstract

Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be determined in vivo using positron emission tomography (PET), for which three fluorine-18 labelled radiotracers have been app...

Subject

Medicine

Amyloid (mycology)

Medical physics

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