Tranexamic Acid in Patients Undergoing Noncardiac Surgery

Devereaux, P.J.; Marcucci, Maura; Painter, Thomas; Conen, David; В. Ломиворотов, В.; I. Sessler, Daniel; T.V. Chan, Matthew; K. Borges, Flávia; José Martínez‐Zapata, María; Yin Wang, Chew; Xavier, Denis; Ofori, Sandra; Ke Wang, Michael; Efremov, Sergey; Landoni, Giovanni; V. Kleinlugtenbelt, Ydo; Szczeklik, Wojciech; Schmartz, Denis; X. Garg, Amit; G. Short, Timothy; Wittmann, Mária; S. Meyhoff, Christian; Amir, Mohammed; Torres, David; Patel, Ameen; Duceppe, Emmanuelle; Ruetzler, Kurt; L. Parlow, Joel; Tandon, Vikas; Fleischmann, Edith; Anne Polanczyk, Carísi; Lamy, André; V. Astrakov, Sergey; Rao, Mangala; Ka Kei Wu, William; Bhatt, Keyur; de Nadal, Miriam; В. Лихванцев, В.; Paniagua, Pilar; J. Aguado, Hector; Whitlock, Richard; McGillion, Michael; Prystajecky, Michael; Vincent, Jessica; W. Eikelboom, John; Copland, Ingrid; Balasubramanian, Kumar; Turan, Alparslan; I. Bangdiwala, Shrikant; Stillo, David; L. Gross, Peter; Cafaro, Teresa; Alfonsi, Pascal; S Roshanov, Pavel; P. Belley‐Côté, Emilie; Spence, Jessica; Richards, Toby; VanHelder, Tomas; F. McIntyre, William; Guyatt, Gordon; Yusuf, Salim; Leslie, Kate

doi:10.1056/nejmoa2201171

Public

Tranexamic Acid in Patients Undergoing Noncardiac Surgery

Published in New England Journal of Medicine • Apr 2, 2022

Authors:

P.J. Devereaux

Maura Marcucci

Thomas Painter

Abstract

BACKGROUND: Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. METHODS: We conducted a trial involving patients undergoing noncardiac surgery. Patients were randomly assigned to receive trane...

Subject

Tranexamic acid

Medicine

Anesthesia

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