Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial

Delany‐Moretlwe, Sinéad; P. Hughes, James; Bock, Peter; Gurrion Ouma, Samuel; Hunidzarira, Portia; Kalonji, Dishiki; Kayange, Noel; Makhema, Joseph; Mandima, Patricia; Mathew, Carrie; Spooner, Elizabeth; Mpendo, Juliet; Mukwekwerere, Pamela; Mgodi, Nyaradzo; Nahirya Ntege, Patricia; Nair, Gonasagrie; Nakabiito, Clemensia; Nuwagaba‐Biribonwoha, Harriet; Panchia, Ravindre; Singh, Nishanta; Siziba, Bekezela; Farrior, Jennifer; Rose, Scott; L. Anderson, Peter; H. Eshleman, Susan; A. Marzinke, Mark; W. Hendrix, Craig; Beigel-Orme, Stephanie; Hosek, Sybil; E. Tolley, Elizabeth; Sista, Nirupama; Adeyeye, Adeola; F. Rooney, James; R. Rinehart, Alex; Spreen, William; Y. Smith, Kimberly; Hanscom, Brett; S. Cohen, Myron; C. Hosseinipour, Mina; Asmelash, Aida; Sehurutshi, Alice; Baguma, Allan; Marais, Anita; Kawoozo, Barbarah; Prudence Malinga, Bongiwe; Gati Mirembe, Brenda; Okech, Brenda; Esterhuizen, Bryan; Murombedzi, Caroline; Gadama, Daphne; Hwengwere, Eldinah; Roos, Elizabeth; S Magada, Elizabeth; Shava, Emily; Piwowar-Manning, Estelle; Tahuringana, Eunice; GS Muhlanga, Felix; Conradie, Francesca; Angira, Frank; Nanyonjo, Gertrude; Kistnasami, Girisha; Mvula, Hazzie; Naidoo, Ishana; Horak, Jaco; Jere, Jane; Moodley, Jeeva; Shin, Katie; Nel, Kerry; Bokoch, Kevin; Birungi, Lilian; Emel, Lynda; Monametsi, Maletsatsi; Sibanda, Marvelous; Mutambanengwe, Mercy; Chitukuta, Miria; Matimbira, Moleen; Bhondai-Mhuri, Muchaneta; Sibisi, Ncamsile; Morar, Neetha; Mudzonga, Netsai; Natureeba, Paul; Richardson, Paul; Musara, Petina; Macdonald, Pippa; Nkambule, Rejoice; Mosime, Repelang; White, Rhonda; Berhanu, Ribka; Ncube-Sihlongonyane, Ritha; Sekabira, Rogers; Siva, Samantha; Pillay, Saresha; Govender, Shamelle; Bamweyana, Sheiala; Nzimande, Siyabonga; Innes, Steve; Dadabhai, Sufia; Samandari, Taraz; Tembo, Tchangani; Lungu Mabedi, Thandie; Chirenda, Thandiwe; Chidemo, Tinashe; Mudhune, Victor; Naidoo, Vikesh; Samaneka, Wadzanai; Agyei, Yaw; Musodza, Yeukai; Fourie, Yolandie; Gaffoor, Zakir

doi:10.1016/s0140-6736(22)00538-4

Public

Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial

Published in The Lancet • Apr 1, 2022

Authors:

Sinéad Delany‐Moretlwe

James P. Hughes

Peter Bock

Abstract

BACKGROUND: Oral pre-exposure prophylaxis has been introduced in more than 70 countries, including many in sub-Saharan Africa, but women experience considerable barriers to daily pill-taking, such as stigma, judgement, and the fear of violence. Safe and effective long-acting agents for HIV preventio...

Subject

Emtricitabine

Medicine

Human immunodeficiency virus (HIV)

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