Immune Checkpoint Inhibitors in Cancer Therapy

Shiravand, Yavar; Khodadadi, Faezeh; Mohammad Amin Kashani, Seyyed; Reza Hosseini‐Fard, Seyed; Hosseini, Shadi; Sadeghirad, Habib; Ladwa, Rahul; J. O’Byrne, Kenneth; Kulasinghe, Arutha

doi:10.3390/curroncol29050247

Public

Immune Checkpoint Inhibitors in Cancer Therapy

Published in Current Oncology • Apr 24, 2022

Authors:

Yavar Shiravand

Faezeh Khodadadi

Seyyed Mohammad Amin Kashani

Abstract

The discovery of immune checkpoint proteins such as PD-1/PDL-1 and CTLA-4 represents a significant breakthrough in the field of cancer immunotherapy. Therefore, humanized monoclonal antibodies, targeting these immune checkpoint proteins have been utilized successfully in patients with metastatic mel...

Subject

Nivolumab

Durvalumab

Medicine

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