The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Sjöblom, Tobias; Jones, Siân; D. Wood, Laura; Williams Parsons, D.; Lin, Jimmy; D. Barber, Thomas; Mandelker, Diana; Leary, Rebecca; Ptak, Janine; Silliman, Natalie; Szabo, Steve; Buckhaults, Phillip; Farrell, Christopher; F. Meeh, Paul; D. Markowitz, Sanford; Willis, Joseph; Dawson, Dawn; K. V. Willson, James; F. Gazdar, Adi; Hartigan, James; Wu, Leo; Liu, Changsheng; Parmigiani, Giovanni; Ho Park, Ben; E. Bachman, Kurtis; Papadopoulos, Nickolas; Vogelstein, Bert; W. Kinzler, Kenneth; E. Velculescu, Victor

doi:10.1126/science.1133427

Public

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Published in Science • Sep 7, 2006

Authors:

Tobias Sjöblom

Siân Jones

Laura D. Wood

Abstract

The elucidation of the human genome sequence has made it possible to identify genetic alterations in cancers in unprecedented detail. To begin a systematic analysis of such alterations, we determined the sequence of well-annotated human protein-coding genes in two common tumor types. Analysis of 13,...

Subject

Biology

Gene

Human genome

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