Results of Two Cases of Pig-to-Human Kidney Xenotransplantation

A. Montgomery, Robert; Stern, Jeffrey; E. Lonze, Bonnie; Tatapudi, Vasishta; Mangiola, Massimo; Wu, Ming; Weldon, Elaina; Lawson, Nikki; Deterville, Cecilia; A. Dieter, Rebecca; Sullivan, Brigitte; Boulton, Gabriella; Parent, Brendan; L. Piper, Greta; Sommer, P.; Cawthon, Samantha; M. Duggan, Erin; Ayares, David; Dandro, Amy; Fazio-Kroll, Ana; Kokkinaki, Maria; Burdorf, Lars; I. Lorber, Marc; D. Boeke, Jef; I. Pass, Harvey; J. Keating, Brendan; Griesemer, Adam; Ali, Nicole; Mehta, Sameer; A. Stewart, Zoe

doi:10.1056/nejmoa2120238

Public

Results of Two Cases of Pig-to-Human Kidney Xenotransplantation

Published in New England Journal of Medicine • May 18, 2022

Authors:

Robert A. Montgomery

Jeffrey Stern

Bonnie E. Lonze

Abstract

BACKGROUND: Xenografts from genetically modified pigs have become one of the most promising solutions to the dearth of human organs available for transplantation. The challenge in this model has been hyperacute rejection. To avoid this, pigs have been bred with a knockout of the alpha-1,3-galactosyl...

Subject

Xenotransplantation

Transplantation

Medicine

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