Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022

H. de Kleine, Ruben; S. Lexmond, Willem; Buescher, Gustav; Sturm, Ekkehard; Kelly, Deidre; W. Lohse, Ansgar; Lenz, Dominic; Hørby Jørgensen, Marianne; behalf of the contributors to the survey, on

doi:10.2807/1560-7917.es.2022.27.19.2200369

Public

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022

Published in Eurosurveillance • May 12, 2022

Authors:

Ruben H. de Kleine

Willem S. Lexmond

Gustav Buescher

Abstract

To detect potential concern about severe acute hepatitis in children, we conducted a survey among 50 ERN RARE-LIVER centres. By 26 April 2022, 34 centres, including 25 transplant centres, reported an estimated median of 3-5, 0-2 and 3-5 cases in 2021, 2020 and 2019 and a mean of 2 (range: 0-8) cases...

Subject

Medicine

Acute hepatitis

Liver transplantation

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