Development and validation of a radiomic model for the diagnosis of dopaminergic denervation on [18F]FDOPA PET/CT

Comte, Victor; Schmutz, Hugo; Chardin, David; Orlhac, Fanny; Darcourt, Jacques; Humbert, Olivier

doi:10.1007/s00259-022-05816-7

Public

Development and validation of a radiomic model for the diagnosis of dopaminergic denervation on [18F]FDOPA PET/CT

Published in European Journal of Nuclear Medicine and Molecular Imaging • May 14, 2022

Authors:

Victor Comte

Hugo Schmutz

David Chardin

Abstract

PURPOSE: FDOPA PET shows good performance for the diagnosis of striatal dopaminergic denervation, making it a valuable tool for the differential diagnosis of Parkinsonism. Textural features are image biomarkers that could potentially improve the early diagnosis and monitoring of neurodegenerative pa...

Subject

Receiver operating characteristic

Logistic regression

Denervation

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