Association of Alzheimer Disease With Life Expectancy in People With Down Syndrome

Florencia Iulita, M.; Garzón Chavez, Diana; Klitgaard Christensen, Maria; Valle Tamayo, Natalia; Plana‐Ripoll, Oleguer; A. Rasmussen, Sonja; Roqué i Figuls, Marta; Alcolea, Daniel; Videla, Laura; Barroeta, Isabel; Benejam, Bessy; Altuna, Miren; Padilla, Concepción; Pegueroles, Jordi; Fernández, Susana; Belbin, Olivia; Carmona‐Iragui, María; Blesa, Rafael; Lleó, Alberto; Bejanin, Alexandre; Fortea, Juan

doi:10.1001/jamanetworkopen.2022.12910

Public

Association of Alzheimer Disease With Life Expectancy in People With Down Syndrome

Published in JAMA Network Open • May 23, 2022

Authors:

M. Florencia Iulita

Diana Garzón Chavez

Maria Klitgaard Christensen

Abstract

Importance: People with Down syndrome have a high risk of developing Alzheimer disease dementia. However, penetrance and age at onset are considered variable, and the association of this disease with life expectancy remains unclear because of underreporting in death certificates. Objective: To asses...

Subject

Life expectancy

Disease

Association (psychology)

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