No association between intravenous fluid volume and endothelial glycocalyx shedding in patients undergoing resuscitation for sepsis in the emergency department

Macdonald, Stephen; Bosio, Erika; I. Shapiro, Nathan; Balmer, Lois; Burrows, Sally; Hibbs, Moira; A. Jowitt, Thomas; Smart, Lisa; Arendts, Glenn; M Fatovich, Daniel

doi:10.1038/s41598-022-12752-x

Public

No association between intravenous fluid volume and endothelial glycocalyx shedding in patients undergoing resuscitation for sepsis in the emergency department

Published in Scientific Reports • May 24, 2022

Authors:

Stephen Macdonald

Erika Bosio

Nathan I. Shapiro

Abstract

Endothelial glycocalyx (EG) shedding is associated with septic shock and described following intravenous (IV) fluid administration. To investigate the possible impact of IV fluids on the pathobiology of septic shock we investigated associations between biomarkers of EG shedding and endothelial cell ...

Subject

Septic shock

Medicine

Sepsis

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