Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease

M. Dedrick, Rebekah; E. Smith, Bailey; Cristinziano, Madison; G. Freeman, Krista; Jacobs‐Sera, Deborah; Belessis, Yvonne; Brown, Anne; A. Cohen, Keira; M. Davidson, Rebecca; van Duin, David; B. Gainey, Andrew; Berastegui, Cristina; R. Robert George, C.; Haidar, Ghady; Ip, Winnie; R. Iredell, Jonathan; Khatami, Ameneh; S Little, Jessica; Malmivaara, Kirsi; McMullan, Brendan; E. Michalik, David; Moscatelli, Andrea; A. Nick, Jerry; Gabriela Tupayachi Ortiz, Maria; Polenakovik, Hari; D. Robinson, Paul; Skurnik, Mikael; A. Solomon, Daniel; F Soothill, J; Spencer, Helen; Wark, Peter; Worth, Austen; T. Schooley, Robert; A. Benson, Constance; F. Hatfull, Graham

doi:10.1093/cid/ciac453

Public

Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease

Published in Clinical Infectious Diseases • Jun 9, 2022

Authors:

Rebekah M. Dedrick

Bailey E. Smith

Madison Cristinziano

Abstract

BACKGROUND: Nontuberculous Mycobacterium infections, particularly Mycobacterium abscessus, are increasingly common among patients with cystic fibrosis and chronic bronchiectatic lung diseases. Treatment is challenging due to intrinsic antibiotic resistance. Bacteriophage therapy represents a potenti...

Subject

Phage therapy

Lytic cycle

Medicine

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