ColabFold: making protein folding accessible to all

Mirdita, Milot; Schütze, Konstantin; Moriwaki, Yoshitaka; Heo, Lim; Ovchinnikov, Sergey; Steinegger, Martin

doi:10.1038/s41592-022-01488-1

Public

ColabFold: making protein folding accessible to all

Published in Nature Methods • May 30, 2022

Authors:

Milot Mirdita

Konstantin Schütze

Yoshitaka Moriwaki

Abstract

ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40-60-fold faster search and optimized model utilization enables prediction of close to 1,000 structures per day on a server with o...

Subject

Computer science

Protein folding

Folding (DSP implementation)

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