Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian Cancer

Xu, Junfen; Fang, Yifeng; Chen, Kelie; Li, Sen; Tang, Sangsang; Ren, Yan; Cen, Yixuan; Fei, Weidong; Zhang, Bo; Shen, Yuanming; Lü, Weiguo

doi:10.1158/1078-0432.ccr-22-0296

Public

Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian Cancer

Published in Clinical Cancer Research • Jun 8, 2022

Authors:

Junfen Xu

Yifeng Fang

Kelie Chen

Abstract

PURPOSE: The heterogeneity of high-grade serous ovarian cancer (HGSOC) is not well studied, which severely hinders clinical treatment of HGSOC. Thus, it is necessary to characterize the heterogeneity of HGSOC within its tumor microenvironment (TME). EXPERIMENTAL DESIGN: The tumors of 7 treatment-naï...

Subject

TIGIT

Serous fluid

Ovarian cancer

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